For drug teams
Know what to test on Monday.
When a programme meets resistance, the Monday-morning question is practical: which experiments get the next slot of lab time and the next vial of patient-derived material? Cytogent helps answer that, one bounded batch at a time.
The allocation problem
Everything competes for the same slots.
Each choice below multiplies the others. The aim is not to test everything, but to test the few things that would change the decision.
- Partner drugs
- Doses and schedules
- Resistant models
- Matched parental controls
- Readouts
- Lab time
- Patient-derived material
- Budget
From question to plate
A decision brief becomes a plate plan.
The workflow starts with the decision, not the data. The brief sets the question, the models and the budget; the plan is the small batch that best serves it, with controls built in.
Decision brief
- Question
- Which partner drug is worth testing against this resistance context?
- Models
- Authenticated resistant models, with matched parental controls
- Budget
- One bounded batch
- Decision
- Go, adjust or stop before the next wave
Plate plan
Who it is for
Built around the people who make the call.
Asset team lead
A defensible go, adjust or stop on a combination strategy, with the evidence behind it.
Translational scientist
Experiments that test a biological hypothesis about resistance, not a screen for its own sake.
Portfolio and business development
To know which signals reproduced before committing capital or a partnership.
Principles
What you can expect from the way we work.
- 01
Bounded experimental batches
Each round is a small, feasible batch chosen for what it can teach, not an open-ended screen.
- 02
Visible uncertainty and abstention
Every ranking carries an uncertainty estimate. Where the evidence is too thin, the system should say so rather than guess.
- 03
Planned reproducibility
A signal counts once it has been seen again: out of batch, or with an orthogonal readout.
- 04
Project-specific data governance
Each sponsor's data stays in its own project, under the terms agreed for that project.
Path to a pilot
Three conversations to a first wave.
- 01
Share the question
The candidate, the resistance context and the decision you face. No confidential structures or patient data at this stage.
- 02
Scope it together
Which models, which readouts, what budget, and what result would change the decision.
- 03
Agree the pilot shape
A bounded first wave with agreed deliverables and go/no-go criteria.
