CRISPR guides designed, checked and documented.
From target to guide.
- Guide design for your target and cell model.
- Off-target review with every site listed.
- Screen analysis with hits ranked and explained.
Guide finds the site · cut · repaired · off-targets reviewed
Three agents, one result.
You ask · agents take turns · results arrive cited · you sign off
Reader long-context LLM
Collects known guides, editing results and target biology.
Analyst code model
Designs guides, scores off-targets and analyses screen data.
Writer drafting LLM
Drafts the validation protocol and the design notes.
What you get back.
Guide set
Guides for your target, each with its scores.
Off-target report
Every close site, with its risk.
Screen analysis
Hits ranked, with the data behind each one.
Protocol draft
A validation protocol ready for review.
Common questions.
How are off-targets reviewed?
Each guide is checked for close matches elsewhere in the genome. The report lists every site found with its risk, so your team can decide which guides to take forward and which to drop.
Can I analyse my own screen data?
Yes. Bring your screen results into the project. The Analyst ranks the hits, notes the method it used and links each finding to the data behind it, so the analysis can be checked and repeated.
Is the protocol ready for the bench?
It is a draft. A scientist reviews it, changes what is needed and signs it off before it is used in the lab. The sign-off is part of the project record.
Works well with.
Protein studies & design
Structure prediction, binding analysis and sequence design, with validation reports.
See this workflowIn-silico studies
Screen, simulate and compare before the bench: docking, ADMET, pathway and PK models.
See this workflowLiterature & evidence
Papers, patents, protocols and registries in one query. Every claim points to its source.
See this workflowBring your next question.
Tell us your field and what you want to do. We set up the workspace around it.
Request access